Sr Staff Mechanical Engineer

Senior Staff Mechanical Engineer (Onsite in Wilsonville, OR)SummaryWe are seeking a Senior Staff Mechanical Engineer to design, build, and test our next-generation automated wet-lab instruments. Based primarily on-site in Wilsonville, OR with partial remote flexibility, this role requires occasional travel to Twist in South San Francisco, CA and to vendor locations.Responsibilities:Use SolidWorks to design multiple instruments that integrate liquid handling, consumable handling, imaging & robotics that meet or exceed System & Hardware requirementsManage and use SolidWorks AI Agents to create new hardware designs leveraging parts & assemblies already in Twist’s PDM environmentSpecify all hardware (off-the-shelf and custom) for the instrumentsWork with other team members to develop and refine requirementsPerform tolerance analysis as neededSupport contract manufacturers and vendors as the Mechanical Technical Lead for your designsWork with other team members to execute and support Factory and Site Acceptance TestingCompile content and hold multiple design reviews as neededUse SolidWorks to design & build test fixtures as needed to de-risk concept features or test sub-systemsSupport Process Systems Engineers as needed during Concept Development and all other project phasesProvide system fluidics and electrical design documentationBuild, debug, calibrate, and verify the instruments with help from technicians and Process System EngineersCreate full models, part files, part drawings, assembly drawings & a BOM for the SystemMaintain full design control and release via 3D- Experience (Dassault Systèmes)Order & track parts for system buildsProvide updated designs for obsolete partsLead hardware design for next-generation custom instrumentation, from concept and feasibility through post-production support.Provide concept architectures for Roadmap developmentRequired Skills:12+ years of experience as a Senior Mechanical Engineer(or higher) and a 4-year degree in mechanical engineering, or 8 years of experience as a Senior Mechanical Engineer (or higher), with a graduate degree in mechanical engineeringExpert in SolidWorks, with a proven record of delivering end-to-end design packages, complete engineering documentation, and fabrication-ready deliverables.Lead Mechanical Engineer of at least 2 benchtop or larger instruments that went into ProductionStrong experience with robotics/mechatronics and specifying electronic devicesExtensive experience designing hardware for fluidics systems, including custom manifolds and integration of pumps, valves, sensors, regulators, etc.Proven track record of collaborating with cross-functional teams—including engineers, scientists, and project managers—across the entire project lifecycle, from initial concept to post-release monitoringExperience managing a CAD PDM systemExcellent communication and writing skills, and the ability to work in a fast-paced team environmentVery strong documentation skillsComfortable working with evolving requirements and a dynamic work environment driving hardware designs for multiple projectsProven ability to perform System IntegrationProven ability to perform Systems Testing, including Factory/Site Acceptance TestingAdditional Bonus Skills:Proficiency in 3DExperienceExperience with mechanical design for optical systemsIn-depth knowledge and use of machine shop tools (band saws, Mill, drill press, sanders)Experience performing electrical and electronics troubleshootingExperience with Altium, Lucid, or other software tools that can be used to create wiring or plumbing diagramsExperience in specifying device controlExperience compiling and releasing QA documentationExperience as an Instrument Technical Lead or Instrumentation Systems EngineerAbout Twist BioscienceTwist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.At Twist Bioscience, we work in service of people who are changing the world for the better.

In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.