## Research Scientist/Engr 4Applylocations: Seattle, WAtime type: Full timeposted on: Posted 13 Days Agojob requisition id: REQ- **Job Description****Field of research:**Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics.**Purpose of the Research Project(s):**The goal of our research is to develop vaccines and therapeutics targeting human pathogens.**Duties and Responsibilities:**20% Structure-based and machine-learning immunogen design for protein subunit and mRNA vaccines based on viral surface glycoproteins (construct design, recombinant expression in mammalian cells, purification, and stability assays),20% Characterize protein antigenicity (binding assays using ELISAs, SPR and biolayer interferometry to evaluate binding kinetics and affinity of antibodies or designed proteins),15% Perform structural studies (high-throughput cryo-electron microscopy of subunit vaccines as well as of complexes between viral glycoproteins and monoclonal and polyclonal antibodies as well as X-ray crystallography), 10% Design and execution of virology assays,10% Analysis of the data to help determining the research strategy,10% Lead projects and/or major project tasks,10% Interactions with collaborators within our network and writing of manuscripts for publication5% Provide guidance and direction to project staff, students and postdocs**Requirements:**Master's Degree in Biochemistry or related field and four years 4 years of experience in related field like: Cryo-electron microscopy, virology assays (pseudotyped virus generation, cellular entry and neutralization assays), protein expression in mammalian cells and purificationEquivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.**Desire:**Expertise in protein and vaccine design, experience in high throughput automation using Beckman Biomek.**Compensation, Benefits and Position Details****Pay Range Minimum:**$99,444.00 annual**Pay Range Maximum:**$122,124.00 annual**Other Compensation:**-**Benefits:**For information about benefits for this position, visit Shift (United States of America)**Temporary or Regular?**This is a regular position**FTE (Full-Time Equivalent):**100.00%
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