My client seeks a **Computational** **Protein Engineer**to build and lead hands‑on experimental programs while leveraging computational tools to accelerate and inform design cycles.
The ideal candidate will take on the following responsibilities:
- Lead experimental design and execution of antibody and protein engineering programs including affinity maturation, multi‑specific antibody development, and de novo binder design
- Drive protein expression, purification, and characterization workflows across multiple formats
- Design and execute binding and functional assays to evaluate and iterate on engineered proteins
- Collaborate with structural biologists and computational scientists to integrate structural insights into experimental programs
- Apply computational tools such as AlphaFold and Rosetta to support and inform wet lab strategies
The ideal candidate will possess the following qualifications:
- PhD in biochemistry, molecular biology, protein biochemistry, or related discipline
- Hands‑on expertise in protein expression, purification, and characterization
- Experience with antibody engineering formats including bispecifics, nanobodies, or related modalities
- Peer‑reviewed publications and/or patents in antibody or protein engineering
- Familiarity with computational design tools (AlphaFold, Rosetta, ProteinMPNN) a plus
- Proven ability to lead technical teams and manage complex, multi‑faced projects
- Outstanding written and verbal communication skills
**This role is onsite in Rockville, MD.**
#J-18808-LjbffrComputational Protein Engineer in rockville at Unknown Company
This position is listed as full time and onsite.