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Validation Engineer - North Carolina

durham, nc • Posted 5 days ago
Onsite Contract Architecture and Engineering Occupations
Validation Engineer - North Carolina

Validation Engineer (CSV Lead)

Location: Durham, North Carolina

Provide computer system validation support for a leading contract development and manufacturing organization (CDMO) specializing in the production of biologics and advanced therapies. You will be responsible for the validation strategy and SDLC documentation for Werum PAS-X MES and Fill/Finish systems, encompassing PLCs, SCADA, MES, and Serialization, within the life sciences manufacturing environment.

Responsibilities
  • Develop and execute validation strategies and plans for Werum PAS-X and PLC-based Fill/Finish systems in compliance with regulatory requirements, industry best practices, and company standards.
  • Systems may include Werum PAS-X, Siemens and Allen-Bradley PLCs, and Aveva Wonderware SCADA.
  • Lead the creation, review, and approval of validation deliverables, including validation plans, protocols, reports, risk assessments, and traceability matrices.
  • Collaborate with cross-functional teams to ensure appropriate requirements gathering and mapping for validation activities.
  • Conduct and oversee FAT (Factory Acceptance Testing), SAT (Site Acceptance Testing), and commissioning activities for BAS and Fill/Finish systems.
  • Perform risk assessments and impact analyses to identify potential issues and develop mitigation plans.
  • Ensure compliance with data integrity requirements and implement measures to maintain data integrity throughout the validation lifecycle.
  • Support and provide guidance to the project team regarding CSV (Computer Systems Validation) principles and best practices.
  • Liaise with external vendors and contractors to coordinate validation activities and ensure adherence to project timelines.
Skills and Experience
  • Bachelor's degree in Engineering, Computer Science, or a related field.
  • Minimum of 5 years of experience in CSV and validation within the pharmaceutical or biopharmaceutical industry.
  • Strong expertise in validating MES and Fill/Finish systems, including experience with PLCs, SCADA, MES, and Serialization.
  • In-depth knowledge of regulatory requirements (FDA, EMA, etc.) and industry standards (GAMP, 21 CFR Part 11) related to CSV and validation.
  • Proven experience in developing and executing validation strategies, plans, protocols, and reports.
  • Solid understanding of SDLC (Software Development Life Cycle) and familiarity with Agile methodologies.
  • Extensive experience with data integrity principles and implementation in CSV activities.
  • Excellent problem-solving skills and the ability to analyze complex systems and processes.
  • Ability to collaborate effectively with cross-functional teams.
  • Proactive mindset with a strong attention to detail and the ability to prioritize tasks effectively.
  • Experience working in a regulated GxP environment.
  • Previous experience in a leadership or mentoring role is highly desirable.

Joining Valspec as a Validation Engineer (CSV) will provide you with an opportunity to make a significant impact in the validation and CSV processes for cutting-edge life sciences manufacturing systems. If you are a highly motivated and detail-oriented professional with a passion for ensuring compliance and data integrity, we encourage you to apply.

Benefits included.

Why Join Valspec?

At Valspec, we offer more than just a job — we provide a career experience rooted in a standout culture, collaborative environment, and a strong sense of ownership. As an Employee Stock Ownership Plan (ESOP) company, every team member has a stake in our success, fostering a shared commitment to excellence and innovation. We also offer a highly competitive benefits package, including:

  • Premium medical coverage
  • 401(k) with company match
  • Tuition reimbursement
  • Unique performance incentives
  • And more — all designed to support your growth, well-being, and future.

Join a team where your contributions matter, your development is prioritized, and your success is shared.

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