US Payroll Strategy Lead — Hybrid, Compliance & Systems

Alnylam Pharmaceuticals, Inc. in Cambridge, MA, seeks a Senior Manager, U.S. Payroll to own the end-to-end U.S. payroll function for all employees. The role combines data, compliance, audits, and system optimization in a hybrid environment.

You will partner with HR, Finance, IT, and Benefits to ensure accurate payroll processing, handle year-end adjustments, and drive process improvements. The ideal candidate has 7–10+ years of payroll experience and a track record of scalable solutions.