Job TitleEssential Functions:Become an expert on the operation of the Roche Single Molecule Sequencing Platform.Perform a variety of sample prep, library, or sequencing and sequencing related experiments on a daily basis, help to analyze and interpret the data.General support of diverse research and development activities.Customer support activities such as monitoring runs, documenting and communicating defects, and following escalation paths to resolve customer issuesContribute to the platform verification team as a member by executing, analyzing, and interpreting the results of platform verification studies.Perform all work using best laboratory practices and maintain a well-organized and concise record of work performed and progress made.Assist engineers with hardware design through testing subcomponentsAnalyze data, derive conclusions, document findings, write SOPs and prepare reports for sharing within and between R&D groupsSetup strong experimental designs while working independently.Troubleshoot instrument failures and seek out specialized help as needed.Responsibilities:This position is responsible for, but not limited to, the following:Develop and deploy a wide range of technologies, including sample extraction, library prep, and sequencing.Develop, execute, and document test cases for verification and validation. Ensures complete and comprehensive coverage of requirements in the test campaigns.Customer support through monitoring of runs, early morning meetings to discuss defects, results and progress, QC of reagents and configuration used for customer, possible travel to customer sites.Support of instrument fleet to learn troubleshooting techniques as needed to assist R&D and to support customersPerform system integration and testing activities and verify system performance through simulation, tests, and measurements. Assess results for applicability, validity, and conformance to product requirements.Work independently with general management direction to drive product development and collaborations to identify opportunities for continuous improvement.Keep supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas.Minimum Requirements:B.S.
or M.S. or PhD degree in the science/chemistry/engineering required and 1-5 years of experience (depending on educational background).Candidates with hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing are encouraged to applyPrevious laboratory experience required.Familiarity with MATLAB, GIT, Python or similar tools for data analysis and/or automation.Previous experience with prototype instruments or DNA sequencing desirable.Previous experience with PCR required.Excellent written and oral communication skills are essential.Demonstrated ability to work well in teams and across scientific disciplines is essential.The candidate should be passionate, self-motivated, and possess a strong desire to acquire on-the-job training.Ideal Candidate:Experience with a variety of laboratory devices and instrumentation, including PCR and automation.In addition to impeccable technical skills, successful candidates possess strong organizational, communication and team skills, and thrive in a fast-paced environmentResourceful and flexible; Fast learner and a self-starter; hard-workingAdept at planning, prioritizing, multi-tasking, organizing and following through, while remaining highly energetic and focused;Straightforward, self-driven, and trustworthy;An individual with experience in biotechnology or medical device development;Strong understanding of DNA & molecular BiologyBreadth of knowledge / cross-disciplinary3+ years of hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing.Knowledge in all phases of NGS workflow such as nucleic acid chemistry, and primer design technologies for gene targets is highly desirable.Proven hands-on troubleshooting experience and skills in wet bench workflows on NGS platform.Experience with statistical tools (e.g. Python/JMP for regression analysis, ANOVA) and Design of Experiments methodology, application of statistical process control is essential.Experience in implementing workflow on semiconductor-based sensing devices or microfluidic devices is desirable.Knowledge in surface chemistry is also desirableStrong analytical, problem-solving, communication, and interpersonal skills and a fast learner.Desired Qualities:Anticipates needs and problems while creating solutions.
Not always instruction-basedDemonstrates a sense of urgency, contagious optimism and a ?can do" attitudeIs curious, inquisitive, innovative, never satisfied with the status quoGreets challenge and change as opportunityCollaborates with others and strong orientation towards teamwork