Sr. Scientist

The Merck Genome Sciences (GS) Immunology translational model system group within the Department of Data, AI, and Genome Sciences (DAGS) is seeking a motivated experimental biologist or pharmacologist to help advance biomarker discovery in Cambridge, MA. Partnering closely with Discovery Immunology, our team develops human-relevant translational assays in support of precision medicine strategies. In this hands-on Scientist I/II role, you will work with immunology scientists, automation engineers, translational researchers, and biobank teams to build and execute scalable, reproducible functional assays using primary human immune cells and patient-derived biospecimens.

Responsibilities

• Develop and execute functional assays using primary human immune cells and translational model systems.
• Collaborate with automation engineers to build robust, scalable, and reproducible assay workflows.
• Support biobank management activities, including biospecimen handling, inventory oversight, sample QC, and integration of patient-derived materials into discovery workflows.
• Work alongside biobank and translational science teams to enable efficient sample access, tracking, and utilization.
• Support biomarker discovery workflows through experimental design, data analysis, and interpretation.
• Present research findings and data to project teams and scientific leadership.

Education

• Master’s degree (MS) or Doctorate (PhD) in molecular, cellular, immunological, or related biological sciences.

Experience

• MS with 8+ years or PhD with 2+ years of experience in molecular, cellular, or immunological sciences.
• Proven hands-on experience in laboratory research and assay development.
• Demonstrated experience working in collaborative, cross-functional research environments.
• Experience with human immune cell culture, primary cell assays, and translational functional readouts preferred.
• Experience working with automation, high-throughput assay platforms, or biobank sample management preferred.

Additional Information

• Key Skills: Strong communication, documentation, and attention to detail, with a strong background in immunology or biomarker discovery.