Sr Principal Scientist

Role

Senior Principal Scientist leading the development of next-generation assay reagents and detection technologies for advanced biomarker analysis platforms, focusing on spatial dyes, bead systems, and bioconjugation chemistry.

Responsibilities

• serve as a scientific expert in assay development, define technology roadmaps, lead innovation in spatial dye architectures, bead surface chemistries, and conjugation strategies
• oversee complex technical investigations and intellectual property generation

Requirements

• Ph.D. in Chemistry, Biochemistry, Molecular Biology, or related field
• 20+ years industry experience in assay or reagent development, with expertise in biomarker detection technologies, multiplexed assays, spatial biomarker applications, and regulated diagnostic environments

Preferred

proven track record translating science into commercial products, patents, high-impact publications, experience with scaling manufacturing, and familiarity with diagnostics (IVD, CLIA, FDA).

High-Value

focus on ultra-sensitive protein detection, multiplexing, spatial biology, and platform innovation supporting disease research and diagnostics.

Work setup

onsite at Billerica, MA, with 10–20% travel for collaborations and conferences; leadership in a fast-paced, collaborative environment emphasizing scientific rigor, innovation, and cross-functional influence.