Senior Principal Scientist, Clinical Research, Thoracic Malignancies

Senior Director (Sr. Principal Scientist) — planning and directing clinical research activities involving new or marketed Oncology medicines across all phases of clinical development.

Responsibilities:

• Evaluate pre-clinical and translational work to generate early clinical development plans and Investigational New Drug (IND) applications.
• Develop clinical development strategies for investigational or marketed Oncology drugs.
• Plan clinical trials (design, operational plans, settings) based on these strategies.
• Monitor and manage conduct of ongoing or new clinical trials.
• Analyze and summarize clinical findings to support decisions on safety/efficacy and for regulatory reporting, clinical study reports, and publication.
• Participate in internal and joint internal/external research project teams for new compounds and further study of marketed compounds.
• Supervise Clinical Scientists executing clinical studies.
• Collaborate with cross-functional experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects.
• Keep corporate personnel informed on study progress and expert scientific input.
• Maintain scientific knowledge via ongoing awareness of new findings/methodologies, identify strong investigators, establish communications with investigators, and attend scientific meetings.
• Author development documents, presentations, budgets, and position papers; facilitate global external collaborations; travel ~20%.

Qualifications:

• Education: M.D. or M.D./Ph.D.
• Required: Industry or senior faculty experience in academia; 3+ years clinical medicine; 3+ years industry drug development or biomedical research in academia; demonstrated scientific scholarship; strong clinical medicine and biomedical research background; strong interpersonal and team skills; outstanding written/verbal communication and presentation.
• Preferred: Board Certified or Eligible in Oncology; prior clinical research experience and prior publication.

Required skills:

• Cancer Research
• Clinical Development
• Clinical Trials
• Cross-Functional Teamwork
• Drug Development
• Oncology Trials

Application deadline listed on posting; job posting effective until 11:59:59PM the day before 09/10/2026 (Requisition ID: R ).