Senior Manager, Marketing KOL Engagement

About Madrigal

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction‑associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality.

Our medication, Rezdiffra (resmetirom), is a once‑daily, oral, liver‑directed THR‑β agonist that targets key underlying causes of MASH. It is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high‑performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Position Overview

The Associate Director, HCP Marketing (KOL Engagement) will play a highly visible role in advancing the launch of Rezdiffra through strategic healthcare professional (HCP) engagement initiatives. In concert with Marketing leadership, this individual will lead the development and execution of impactful peer‑to‑peer education and thought leader engagement programs designed to elevate scientific exchange, strengthen advocacy, and accelerate HCP adoption.

Key Responsibilities

• In concert with Marketing leadership, drive the strategy and execution of HCP engagement and peer‑to‑peer education initiatives aligned with brand priorities and commercial objectives.
• In collaboration with cross‑functional partners, lead speaker bureau strategy and operations, including speaker engagement, training, program execution, content collaboration, compliance, and performance analytics.
• Support regional and local congress engagement initiatives, including product theaters, KOL engagement opportunities, and field‑facing educational programs.
• Develop and execute advisory board strategies to generate actionable customer insights and inform brand strategy.
• Partner closely with the Thought Leader Liaison (TLL) team to translate field insights into meaningful commercial opportunities.
• Collaborate cross‑functionally with HCP Marketing, Sales, Medical Affairs, Regulatory, Legal, Compliance, PRC/MLR, Analytics, and Market Research teams to ensure aligned and compliant execution.
• Manage agency partners, budgets, timelines, and operational execution with a focus on excellence, agility, and impact.
• Leverage analytics and customer insights to continuously optimize engagement strategies and program performance.

Required & Desired Qualifications

• Bachelor’s degree required; MBA or advanced degree preferred.
• 8-10 years of biopharmaceutical commercial and/or marketing experience.
• Proven experience leading speaker bureau programs, peer‑to‑peer education initiatives, advisory boards, and KOL engagement strategies.
• Experience supporting specialty product launches within dynamic commercial environments; Subpart H launch experience preferred.
• Strong understanding of pharmaceutical promotional regulations and experience operating successfully within regulated environments.
• Exceptional strategic thinking, project leadership, communication, and stakeholder management skills.
• Demonstrated ability to translate clinical data and customer insights into compelling educational initiatives.
• Experience in liver disease, hepatology, gastroenterology, endocrinology, or related specialty markets preferred.
• Thrives in fast‑paced, entrepreneurial environments with a strong sense of ownership and accountability.
• Domestic travel up to 35%, including occasional weekends.
• Hybrid role based in Conshohocken, PA or Waltham, MA (3 days onsite weekly).

Benefits and Compensation

Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs, and market demands. As of the date of this posting, the pay range for this position is $182,000 to $222,000 per year. Employees also receive equity, flexible paid time off, medical, dental, vision, life/disability insurance, and 401(k) offerings (traditional, Roth, and employer match).

Full‑time employees are eligible for a comprehensive benefits suite, additional voluntary benefits, mental health support through our Employee Assistance Program, and compatibility with applicable federal, state, and local laws.

Accommodation Statement

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact

Equal Opportunity Employer

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Application Process

Applications are being accepted on an ongoing basis and can be submitted through our Careers site.