Senior Associate Scientist, Oligonucleotides

Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an Associate Scientist/Senior Associate Scientist to join our Nucleic Acid Therapeutics group, supporting drug discovery and technology development in the field of oligonucleotide therapeutics such as siRNAs and antisense oligonucleotides. In this role, you will develop assays and execute high-throughput screenings of hundreds to thousands of candidate molecules, while collaborating with your team to advance oligonucleotide therapeutic programs. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Location: Tarrytown, NY

Work model/flexibility: Onsite

Discover your role:

• Develop assays to enable high-throughput oligonucleotide library screenings
• Execute high-throughput screening of hundreds to thousands of candidate molecules
• Perform cell culture optimization, bDNA, RT-qPCR, cell line generation, and transfection optimization
• Design probes and conduct compatibility tests, along with western blot analysis
• Work with automated or semi-automated processes, including liquid handlers and instruments such as KingFisher and QuantStudio
• Independently execute and refine techniques and technologies with general guidance
• Multi-task and shift priorities based on communicated department needs
• Thrive in a fast-paced environment, staying detail-oriented, organized, and eager to learn new techniques

This role requires:

• Bachelor's degree required
• Master's degree preferred 2+ years of industrial experience in a relevant field highly appreciated Ability to independently execute and refine techniques with general guidance, multi-tasking across shifting priorities Strong organizational and communication skills, with the ability to work well in a team Preferred: experience with automated/semi-automated liquid handlers, KingFisher, and QuantStudio Preferred: knowledge of oligonucleotide chemistry and RNA biology

Salary Range (annually) $80,300.00 - $131,100.00

Benefits:

• Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

Regeneron is committed to building a workplace with an inclusive culture.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.

For additional information about Regeneron benefits in the U.S., please visit For other locations, additional information will be provided during the recruitment process.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Regeneron’s medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.