We’re looking for a detail‑oriented Wet Lab Scientist to support a high‑priority binder screening campaign for engineered T‑cell therapies. You’ll operate at the bench, driving the transition from binder discovery to functional validation.
Do you have the following skills, experience and drive to succeed in this role Find out below.
What You’ll Do
- Engineer primary human T cells using non‑viral delivery (mRNA, transposon DNA; electroporation/nucleofection)
- Monitor viability, recovery, and receptor expression prior to functional assays
- Run high‑throughput screening assays for binder affinity and function
- Maintain/expand primary T cells and Jurkat lines using impeccable aseptic technique
- Perform multi‑color flow cytometry; analyze data in FlowJo
- Execute functional assays: cytotoxicity (IncuCyte, LDH), cytokine profiling (ELISA/MSD/Luminex), proliferation (CFSE)
- Document all work in ELN with precision for data integrity
What You Bring
- BS/MS in Immunology, Molecular Biology, Bioengineering, or related field
- 2+ years hands‑on wet lab experience (industry xhqgsiq preferred)
- Strong aseptic technique; experience isolating primary T cells from PBMCs
- Expertise in flow cytometry acquisition & analysis (required)
- Experience with non‑viral transfection methods; comfort with automation/robotics a plus
- Clear communication and ability to present data in fast‑paced sprint meetings
Scientist in san diego at Unknown Company
This position is listed as full time and onsite.