Position Title: Scientist II
Work Location: North Chicago, IL 60064
Assignment Duration: 12 Months
Work Arrangement: 100% Onsite
Position Summary:
The incumbent will help develop and optimize protocols for 3D bioreactor cell culture work using a human adherent primary cell line coupled with microcarriers as well as more traditional 2D cell culture. This role will focus on bioprocess optimization and secretome characterization.
Background & Context:
The Skincare Aesthetics Bioprocess Innovation Center (SABIC) is in North Chicago and is a joint effort between Skincare Aesthetics R&D and Bioprocess Engineering R&D towards bioprocess discovery related to cell-based technologies for topical skincare.
Key Responsibilities:
- Conduct laboratory experimentation for cell culture and bioprocess development, optimization, and scale-up in a quest to innovate new cell-based active materials and processes.
- Stirred-tank bioreactor bioprocess development and optimization.
- Support scale-up from 100 mL to 15+L cultures.
- Evaluate and optimize feeding process, including continuous perfusion feed system.
- Daily checks and maintenance through bioprocess experiments (like glucose/lactate monitoring, viability and proliferation tracking etc.).
- Perform bioassays to characterize secretome products (like ELISA, flow cytometry, immunofluorescent imaging etc.).
- Assist with sample prep and working with collaborators for secretome characterization.
- Assist in analysis and interpretation of proteomic, lipidomic, and metabolomic data.
- Regular updates through oral presentations and written technical reports.
Qualifications & Experience:
- Degree in Chemical Engineering, Bioengineering, Biology, or other relevant scientific discipline with BS and typically 5+ years of experience, MS and typically 2+ years of experience, or PhD and typically 0+ years of experience in industry.
- Must have strong fundamentals in cell biology.
- Must have hands-on experience with cell culture.
- Desirable to have experience working with bioreactors, process optimization, and scale-up.
- Proven ability to adjust accordingly in response to shifting priorities.
- Proven ability to design and carry through multiple experiments in parallel.
Scientist II in north chicago at Unknown Company
This position is listed as full time and onsite.