Scientist I

Level of Experience : Entry Level

Employment Type : Contract on W2 (Need US Citizens or GC Holders or GC EAD or OPT or EAD or CPT) Work days/hours: M - F 8:30am -- 5pm

Position : Scientist I

Location : Sparks, MD

Duration : 12 Months

Total Hours/week : 40.00 rate:$20-30/hr

1st Shift

Client : Medical Devices Company

Level of Experience : Entry Level

Employment Type : Contract on W2 (Need US Citizens or GC Holders or GC EAD or OPT or EAD or CPT) Work days/hours: M - F 8:30am -- 5pm

Job Description

• Works within a team to provide synthetic oligonucleotides through the use of automated oligonucleotide synthesizers and Liquid Chromatography systems which support the development of automated assays using nucleic acid isolation and real-time amplification/detection technology within the Molecular Diagnostic plants.

Duties And Responsibilities

• Follows established protocols for the synthesis and purification of oligonucleotides used in manufacturing and R&D.


• Follows established protocols for the preparation of buffers used in the oligonucleotide and conjugation processes.


• Follows established protocols for protein conjugation procedures.


• Contributes to the completion of goals associated with specific oligonucleotide process optimization projects.


• Contributes to developing solutions and providing recommendations as to the appropriate course of action to technical problems associated with the preparation of synthetic oligonucleotides.


• Provides documentation and validation support in execution of synthesis and/or purification process changes.


• Performs laboratory work and documentation in accordance with GMP, GLP and company guidelines.


• Perform tasks under general supervision.

Qualifications

• Basic understanding in the use of the liquid chromatography manual or automated systems.


• Basic understanding of chromatography theory and hands‐on experience with HPLC


• (High Performance Liquid Chromatography).


• Excellent verbal and written communication skills are necessary together with the


• ability to interact effectively in team and cross‑functional environments.


• Understanding of the GMP and GLP laboratory guidelines.


• Optional experience includes the use of a DNA (oligonucleotide) and/or Peptide synthesizer and having an understanding of the oligonucleotide synthesis chemistry.


• Understanding of Lean manufacturing tools highly beneficial.

Education And Experience

• Minimum of a Bachelor’s Degree in Biochemistry, Chemistry, Molecular Biology or related discipline.


• Prefer a minimum of 1 year of industrial or academic experience in the synthesis and/or purification of oligonucleotides.