Postdoc Research Scholar- Nascone-Yoder Lab

Postdoc Research Scholar – Nascone-Yoder Lab

Department ID - Department of Molecular Biomedical Sciences

Position Overview

The Postdoctoral Researcher will conduct independent research focusing on the development of anatomical left-right asymmetry. Specifically, the incumbent will investigate the cellular and molecular mechanisms of left-right asymmetric organ morphogenesis within the developing digestive tract. Research methodologies will utilize advanced gene misexpression strategies (CRISPR/morpholino oligonucleotides), transcriptomics (bulk and/or spatial), 3D imaging modalities (nano‑CT), and/or computational modeling (CompuCell3D).

Core Competencies & Responsibilities

• Project Leadership: Demonstrated ability to independently lead, manage, and execute complex research projects while working effectively within an interdisciplinary team environment.
• Communication & Collaboration: Excellent oral and written communication skills, with a proven track record of successful scientific collaboration.

Technical Expertise & Preferred Qualifications

• Advanced Research Methodologies: Demonstrated expertise in microscopy, image processing/analysis, gene editing, immunostaining, and/or molecular biology.
• Scholarly Output: A strong record of publication in peer‑reviewed scientific journals, reflecting the ability to synthesize and disseminate research findings.

Research Design and Execution

• Independent Experimentation: Independently design and conduct research experiments to investigate developmental processes.
• Advanced Methodologies: Utilize advanced technical methodologies, including gene expression analysis, cell lineage tracing, and manipulation of genetic pathways.
• Model Organism Care: Manage, work with, and care for living model organisms (e.g., mouse, Xenopus) as required by research protocols.

Data Analysis and Interpretation

• Technical Analytics: Analyze complex experimental data using advanced techniques such as microscopy imaging and bioinformatics.
• Data Visualization: Generate high‑quality figures, charts, and diagrams to clearly present research data.
• Results Interpretation: Interpret experimental results to draw meaningful, data‑driven conclusions about the mechanisms of development.

Publication and Dissemination

• Manuscript Production: Prepare and draft scientific manuscripts for publication in peer‑reviewed journals, managing data presentation, discussion text, and subsequent revisions.
• Research Presentation: Disseminate research findings at national and international conferences, as well as within internal collaborative networks.
• Intra‑Lab Support: Collaborate with laboratory colleagues and contribute to ongoing projects involving alternative organ systems.
• Cross‑Disciplinary Partnership: Partner with researchers across scientific disciplines to exchange expertise and advance shared research aims.

Other Work and Responsibilities

• Grant Writing Support: Support the development of institutional and federal grant proposals by conducting literature reviews and drafting experimental design sections.
• Professional Development: Attend scientific conferences or technical courses to present findings and actively expand research skill sets.
• Laboratory Management & Mentorship: Maintain accurate laboratory records, manage research supply inventories, and mentor or train junior researchers and undergraduate students.

Work Schedule

9:00am-5:00pm Monday-Friday; Occasional Evening and Weekend Hours

Requirements and Preferences

• Ph.D. in Developmental/Molecular Biology: Or a closely related scientific field.
• In Vivo Research & Animal Model Handling: Extensive experience with common developmental biology models, small animal handling, and specialized care.
• Advanced Microscopy & Image Analysis: Hands‑on experience with confocal microscopy, image processing, and morphometrics.
• Molecular & Genetic Proficiency: Demonstrated expertise in gene editing, misexpression, and immunostaining techniques.
• Lab Operations, Autonomy, & Teamwork: Strong knowledge of compliance/data management, with a proven ability to lead projects independently and collaborate effectively.

Valid NC Driver's License

No

Recruitment Details

Anticipated Hiring Range $60,000-$65,000

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