Oligonucleotide Discovery Chemistry Lead (Preclinical)

GSK’s Cambridge, MA team is seeking a PhD-trained chemist to help establish pre-clinical oligonucleotide conjugation capabilities. You will develop conjugates with ASOs, siRNA, SSO, and RNA editors, advancing small molecule and lipid chemistries at scale.

The role is full-time on-site, with hands-on synthesis, SOP development, and cross-team collaboration. Candidates should have 3+ years post-PhD in chemistry or chemical biology, plus 2+ years in modern synthetic methods and oligonucleotide