Medical Director – Clinical Development, Aging

• Provide clinical and scientific leadership for clinical and translational studies and asset-level programs
• Contribute to assessment of mechanisms and targets, target validation, life-cycle expansion, and innovative clinical development opportunities
• Develop and execute clinical development plans and align translational and clinical plans and study designs with project strategies
• Develop sections of core regulatory documents
• Generate data and evidence on efficacy, safety, differentiation, and route to medicine
• Define and deliver clinical pillars of the translational table
• Deliver clinical development and study timelines and endpoints, including pharmacology, mechanism, and clinical efficacy endpoints
• Establish relationships with Biology, Translational Sciences, Commercial, Regulatory, Clinical Operations, Market Access, Medical Affairs, and Statistics counterparts
• Provide oversight of R&D evidence-generation strategy and study delivery
• Contribute to indication planning, target validation, translational plans, candidate selection, and the early medicine profile
• Design clinical development plans, protocols, and associated documents across development phases
• Support regulatory interactions, briefing documents, presentations, and responses
• Provide medical monitoring and safety oversight of study participants with the Pharmacovigilance Physician
• Ensure medical governance, scientific integrity, and subject safety across studies
• Lead the Clinical Matrix Team for a program
• Serve as the clinical point of contact for indications, investigational agents, and clinical studies
• Lead end-to-end clinical development strategy for early programs and contribute to later stages
• Engage regulatory agencies, key opinion leaders, clinical investigators, internal review boards, and Protocol Review Boards
• Assist with clinical evaluation of business development opportunities
• Monitor research, trial methodologies, competition, and regulatory developments
• Identify transformational opportunities and contribute to Medicine Profile clinical components
• Solve study and clinical development challenges and influence project and departmental decisions
• Create innovative scientific and technical solutions using new learning and digital tools
• Inspire others, manage conflict, and collaborate across the matrix
• Analyze complex data, anticipate obstacles, assess risks, and make informed decisions

Requirements

• Medical Degree
• Completion of formal postgraduate clinical training, clinical residency, or specialty training in Internal Medicine, Pathology, or similar
• Demonstrated experience in clinical trial conduct, including medical monitoring, safety review, and clinical data interpretation
• Strong working knowledge of clinical development processes, GCP, ICH guidelines, and global regulatory frameworks
• Ability to apply clinical judgment to study design, patient safety, and real-time medical decision-making
• Experience operating within cross-functional matrix teams in a pharmaceutical, biotechnology, or academic clinical trial environment
• Strong scientific communication skills and ability to translate clinical data into clear insights
• Preferred: advanced specialty training, fellowship, or country-equivalent higher-level qualification leading to formal specialist recognition, board certification, or country-specific professional designation
• Preferred: pharmaceutical or biotechnology clinical development experience across early-phase studies
• Preferred: clinical experience in relevant specialties or therapeutic areas with direct clinical research or drug development exposure
• Robust knowledge of aging research priorities, public health needs, competitor landscape, clinical practice trends, and treatment guideline evolution
• Knowledge and experience executing clinical and/or translational studies, generating and analyzing human translational data, and conducting preclinical biological experiments
• Experience working with global regulatory agencies and managing global clinical trials
• Prior experience contributing to IND, CTA, NDA, BLA, or MAA submissions
• Experience engaging Key External Experts, investigators, and scientific collaborators in aging disease areas
• Ability to work collaboratively in cross-functional teams and matrix environments to design and execute trials to regulatory standards

Core Competencies

Demonstrates expertise in clinical development processes, regulatory frameworks, and scientific communication, with a strong focus on patient safety and innovative study design. Proven ability to lead cross-functional teams and engage with regulatory agencies to drive clinical and translational studies.