Lead Downstream Modeling Scientist, Biologics

Merck & Co., Inc. is seeking an Associate Principal Scientist to join the DSCS Process Modeling & Analytics team in a hybrid role in the U.S.

This senior scientist will apply mechanistic modeling to downstream processes, including preparative chromatography, and guide resin and mode selection, gradient design, and scale‑up decisions. They will partner with DSP scientists and process engineers, build validated models, mentor junior staff, and drive the roadmap for mechanistic simulation across