Lab Specialist Intermediate or Senior , Department of Surgery

Lab Specialist Intermediate or Senior, Department of SurgeryThe Brayman Lab in the Department of Surgery at the University of Virginia is seeking a Laboratory Specialist Intermediate or Senior to perform and assist with studies investigating the underlying mechanisms of type 1 diabetes and recurrence of diabetes in various murine models of diabetes. The position will also support human pancreatic islet isolations in the GMP islet isolation facility.Responsibilities include working with mice and performing/assisting with in vitro and in vivo experiments related to ongoing studies, including:Working with murine models of diabetes, including mouse islet isolation and transplantationSurgical proceduresIsolating isletsMeasuring mouse blood glucose levelsCollection of mouse tissue, serum, and blood, including collection of mouse tissue and blood for proteomic studiesAssistance with collection and entry of data in electronic mediaSupporting daily lab activities, maintenance, and general laboratory upkeepOrdering/purchasing materials and supplies, including purchasing through the procurement systemOther duties as assignedThe ideal candidate is an enthusiastic team-oriented individual with a willingness to learn, collaborate, and take on new challenges. Candidates must be able to:Perform routine laboratory data analysis and research proceduresIndependently prepare solutions and reagentsPerform or learn to work with animal models (including surgical techniques; training provided if necessary)Work diligently with strong attention to detailAnalyze and organize work procedures; plan and execute tasks/experiments; interpret and report findings, writing skillsWork a flexible schedule when requiredTrain in and comply with BSL-2 proceduresDemonstrate reproducibility and strong critical thinking skillsMinimum Qualifications:Education: Bachelor's degree required.Experience: 3+ years of relevant experience.Preferred Qualifications:Experience working actively in a research laboratory; experience in standard cell biology techniques and murine workFlow cytometry and CyTOFProtein purification (including immunoglobulins such as IgM) and chromatographyExperience with Akta go FPLC systemProteomicsExperience with mass spectroscopy (LC-MS), glycan preparation, data analysisImmunoassays, including ELISAsElectrophoresis and Western blotPCR, RT-PCRDNA and RNA extractions for NGS, RNAseq / scRNAseq / cfRNAseqTissue culture / in vitro cell cultureHistology analysis and immunostaining of tissue sections to back up imaging mass cytometryImmunohistochemistry, Immunofluorescence, Immunocryohistochemistry.Stem cells and organoidsImaging mass cytometryConfocalExperience in R and Python, with additional experience in downstream pipeline analysis and additional expertise in statistical and data analysis softwarePhysical Demands: This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.Salary Range: Salary will be commensurate with education and experience.Position Type & Work Location:This is an exempt-level, benefited position.

Learn more about UVA benefits.This is a restricted position, which is dependent on funding and is contingent upon funding availability.This position has a term limit of 1 year after which continued employment will depend on department need and funding.This position is based in Charlottesville, VA, and must be performed fully on-site.About UVA and the Community: To learn more about UVA and in the Charlottesville area, visit UVA Life and Embark CVA.Application Timeline: Application review will begin after April 27, 2026.Additional Requirements:Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.This position will not consider candidates who require immigration sponsorship now or in the future.How to Apply: Please apply online, by searching for requisition number R . Internal applicants may search and apply for jobs on the UVA Internal Careers website. Complete an application with the following documents:ResumeCover LetterUpload all materials into the resume submission field. You can submit multiple documents into this one field or combine them into one PDF.

Applications without all required documents will not receive full consideration. Reference Check Process: Reference checks will be completed by UVA's third-party partner, SkillSurvey, during the final phase of the interview. Five references will be requested, with at least three responses required.For questions about the application process, please contact Jon Freeman, University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities.

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