Lab, Research & Operations ManagerBecoming is building a Developmental Intelligence™ platform that combines biology, engineering, and AI to understand, model, and guide development. We design and operate integrated biological and technological systems that enable new approaches to tissue generation, regenerative medicine, and therapeutic discovery.Our team brings together expertise across developmental biology, tissue engineering, hardware, software, and operations. We are mission-driven, highly collaborative, and focused on building foundational capabilities that can scale from early research through clinical and translational applications.We are seeking a highly capable Lab, Research & Operations Manager to join our growing team in San Francisco.
This is a manager-level, hands-on role that combines in vivo research execution with ownership of laboratory operations, safety, compliance, and operational excellence.This role is a steward of lab health and safety and a central operational leader. You will establish and maintain SOPs, ensure inspection-ready lab and vivarium operations, manage projects across teams, and track KPIs that keep the organization running safely, efficiently, and on schedule.The ideal candidate thrives in an early-stage environment, enjoys both bench work and systems-building, and takes pride in creating order, safety, and repeatability in complex scientific operations.Lab, Vivarium & Safety OperationsOwn day-to-day laboratory and vivarium operations, ensuring a safe, clean, compliant, and inspection-ready environment at all timesServe as a primary steward of lab health and safety, including biosafety, chemical hygiene, animal welfare, waste management, and equipment safetyEstablish, document, implement, and continuously improve Standard Operating Procedures (SOPs) covering lab operations, vivarium workflows, animal handling, biosafety, equipment use, and waste disposalEnsure SOPs are version-controlled, actively followed, trained on, and audited, not just writtenLead onboarding and recurring training for staff on SOPs, lab safety, and compliance requirementsSupport and coordinate IACUC, EH&S, and internal audits, inspections, and protocol updatesCoordinate equipment maintenance, calibration schedules, certifications, and vendor service visitsManage animal deliveries, cage cleaning coordination, and accurate animal care documentationHandle, breed, and maintain animal colonies and perform tissue collection as requiredResearch & Histology SupportPerform mouse embryo dissections and tissue isolations from early developmental stagesConduct in vivo procedures including IV, IP, and PO dosing; necropsy; tissue collection; and sample processing in rodent modelsMonitor animal health and maintain accurate experimental records in compliance with ethical and regulatory standardsValidate and perform in vitro assays to evaluate tissue-engineered constructsPerform primary and iPSC cell culture using aseptic techniquesPrepare samples for flow cytometry, RNA sequencing, and histological stainingAnalyze and interpret histological and experimental data and present findings to cross-functional teamsCollaborate closely with research, engineering, and manufacturing teams to advance therapeutic programsOperations, Project Management & KPI TrackingOwn operational project management across lab, vivarium, and biomanufacturing workflowsCreate and maintain lightweight project plans, timelines, and dependencies for research, infrastructure, and operational initiativesDefine, track, and report key operational KPIs, including but not limited to:Lab uptime and equipment availabilityInventory accuracy and stockout ratesSafety incidents and corrective actionsAnimal colony health, utilization, and throughputExperiment turnaround timesBuild and maintain dashboards or reporting systems (e.g., spreadsheets, Notion, Airtable, or similar) to provide visibility into operational performanceIdentify operational bottlenecks and inefficiencies and drive process improvements through executionPartner with leadership and cross-functional teams to align operational execution with company priorities and milestonesPurchasing & Inventory ManagementManage ordering of lab supplies, reagents, consumables, and office materialsMaintain accurate, real-time inventory systems and optimize stock levelsCoordinate with vendors and sales representatives on delivery timelines, backorders, and issue resolutionEnsure safe storage, labeling, and tracking of chemicals, biologicals, and controlled materialsBiomanufacturing & Hardware SupportOperate biomedical-grade resin 3D printersPerform post-processingAssist with assembly, bonding, tubing, and fittingsConduct testing and basic quality control checksSterilize equipment and components in accordance with safety and quality standards