DMPK Scientist: PK/PD Modeling for RNA Therapies

Alnylam Pharmaceuticals, Inc. in Cambridge, MA is seeking a DMPK Scientist to design and interpret in vitro and in vivo ADME and PK/PD studies for siRNA and other modalities, informing human dose projections and candidate selection.

You will build quantitative models and simulations using Phoenix WinNonlin, Monolix, and R, integrate PK/PD and biomarker data, collaborate with cross-functional teams, and prepare analyses and regulatory submissions.