Director, Commercial Supply Chain

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Job Summary

IDEAYA is a precision medicine oncology company committed to discovering, developing, and commercializing transformative therapies for cancer. Our approach integrates small‑molecule drug discovery, structural biology, and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first‑in‑class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody‑drug conjugates (ADCs) for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized, with the goal of altering the course of disease and improving clinical outcomes for patients with cancer. When you’re at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients.

Location: South San Francisco, CA.

Position Summary

We are seeking an experienced, strategic, resourceful, and highly motivated Director, Commercial Supply Chain to lead end‑to‑end commercial supply planning and operational launch readiness for IDEAYA Biosciences’ first commercial product, Darovasertib, ensuring product availability, compliant distribution, and robust performance management. This role requires an individual with demonstrated ability to operate effectively in a fast‑paced and evolving environment, engage cross‑functionally (Quality, CMC, Commercial, Regulatory, Accounting/Finance, IT), and communicate clearly and proactively across internal and external stakeholders. The ideal candidate will be a collaborative leader and critical thinker who can operate with autonomy, manage complex drug supply chains, and translate commercial demand forecasts into actionable supply strategies. This position reports to the VP, Clinical and Commercial Supply Chain and is based in our South San Francisco headquarters; on‑site presence is required four days per week.

Job Description

What you’ll do:

• Own commercial supply strategy and launch readiness plans, ensuring supply chain readiness for launch and lifecycle supply.
• Develop and maintain integrated demand/supply plans, production schedules, capacity models, inventory strategy, and scenario analyses.
• Lead and drive S&OP cadence: monthly supply reviews, risk/opportunity assessments, mitigation actions, and executive‑ready reporting.
• Lead end‑to‑end inventory management (GxP and SOX compliant) across the commercial supply chain, including inventory policy setting, reconciliation, cycle counting oversight, expiry tracking, and alignment with demand and production plans; act as system business owner for NetSuite Inventory Module.
• Manage external network execution; align campaign plans and batch execution to forecasts and contractual commitments.
• Partner with Finance/Accounting for reconciliations, chargebacks, rebates, etc.
• Oversee commercial packaging readiness: secondary packaging/labeling, serialization strategy/execution, artwork lifecycle coordination, shipping lane validation, cold‑chain controls, and exception management.
• Serve as the primary point of contact for commercial packaging, labeling, logistics, and storage vendors and develop a governance process for effective management of these vendors.
• Build and monitor KPIs/dashboards (service level, plan adherence, capacity utilization, inventory health) and lead continuous improvement of planning tools/processes.
• Partner with Quality/Regulatory/CMC to ensure GxP‑compliant release and distribution readiness and alignment to registration timelines.
• Support budgeting/forecasting for commercial supply activities, including scenario‑based financial impact modeling.

Requirements

• BA/BS in Supply Chain, Engineering, Life Sciences (advanced degree preferred).
• 10–12+ years in biotech/pharma supply chain, including 3+ years commercial and/or late‑stage launch readiness experience.
• Experience serving as a California Board of Pharmacy–designated representative (DR) for manufacturer, wholesaler, or distributor licensing, or willingness to serve in this role.
• Proven experience managing external manufacturing and supply partners.
• Strong understanding of GMP/GDP, regulatory timing impacts on supply, and global distribution logistics.
• Advanced planning/analytics skills (Excel and/or supply planning tools); strong cross‑functional leadership and communication.
• Comfortable operating in ambiguity; able to build processes “from the ground up.”
• The successful candidate will be a team player with integrity, a commitment to quality, and the ability to think critically and creatively in a fast‑paced, changing environment.
• Proficiency in Microsoft Office Suite and experience with collaborative platforms (e.g., SharePoint, Box) and NetSuite inventory systems.
• Willingness and ability to travel domestically and internationally as needed.

Total Rewards

Along with our inspiring mission and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay‑for‑performance philosophy. Employees are eligible to be considered for merit‑based salary increases, company discretionary short‑term incentive plan participation, and company discretionary stock option awards. Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company‑paid for employees and 90% for dependents), 401(k), ESPP, and wellness programs.

The expected salary range for the Director, Commercial Supply Chain is $203,000 – $251,000. Final salary will depend on location, experience, education, and performance during the interview process.

All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct. Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or company policy through appropriate channels.

IDEAYA is an equal‑opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.

We are committed to providing reasonable accommodations to qualified individuals with disabilities. If you need assistance or an accommodation due to a disability, please contact .