Associate Medical Director

Associate Medical Director - Clinical Science, Neuroscience

A leading pharmaceutical organization is seeking an Associate Medical Director, Clinical Science to support clinical development programs within its Neuroscience Therapeutic Area . This senior clinical development role will lead study strategy, clinical science activities, medical decision-making, and cross-functional collaboration across global development programs.

Role Overview

The Associate Medical Director will drive the clinical strategy for assigned pipeline compounds, integrating medical, scientific, regulatory, and commercial considerations into clinical development plans. The role will work closely with multidisciplinary and multinational teams and contribute to high-impact development decisions, including study design, data interpretation, and go/no-go recommendations.

Key Responsibilities

• Lead or co-lead clinical and study execution teams supporting global development programs.
• Contribute to asset strategies, Clinical Development Plans, clinical protocols, and study execution activities.
• Evaluate ongoing clinical data and assess its medical and scientific significance.
• Make recommendations regarding development strategy, study design, timelines, and potential go/no-go decisions.
• Oversee the preparation, approval, and execution of clinical study protocols and related documentation.
• Interpret clinical study results from both scientific and patient-focused medical perspectives.
• Provide medical monitoring and assess protocol conduct and individual subject safety.
• Partner with Pharmacovigilance on overall study and compound safety assessments.
• Provide scientific and medical leadership to clinical scientists and cross-functional teams.
• Engage with key opinion leaders and contribute to regulatory and scientific interactions.
• Lead or support internal task forces and global cross-functional teams.
• Participate in business development and due diligence activities, including assessment of potential clinical programs and partnerships.
• Contribute to clinical development strategies for alliance and licensing opportunities.
• Mentor, develop, and support clinical science staff.

Requirements

• MD, MD/PhD, or internationally recognized equivalent medical degree.
• At least 3 years of clinical research experience within the pharmaceutical industry, CRO, healthcare consulting, biomedical/clinical academia, or a combination of these.
• Strong clinical development and medical decision-making capabilities.
• Excellent strategic, communication, interpersonal, negotiation, and influencing skills.
• Demonstrated ability to drive decisions within multidisciplinary, multinational matrix teams.
• Strong problem-solving and strategic planning abilities.
• Knowledge of regional and global regulatory requirements.
• Knowledge of GCP/ICH principles.

Preferred Qualifications

• Previous experience leading multidisciplinary matrix teams.
• Experience designing and executing first-in-human and early proof-of-concept clinical trials .
• Neuromuscular disease
• Neurodegenerative disease
• Previous experience in clinical development strategy and study execution.
• Location: Cambridge, Massachusetts
• Employment Type: Full-time
• Workplace: Hybrid
• Industry: Pharmaceutical / Biotechnology
• Specialization: Clinical Development / Neuroscience
• Travel: Approximately 10-20%, including occasional international travel

Key Focus Areas

Clinical Development | Neuroscience | Medical Affairs | Clinical Science | Drug Development | Clinical Trials | Regulatory Strategy | Medical Monitoring | Clinical Research | Pharmaceutical R&D | Business Development