Associate Director, Translational PK/PD

The Translational PK/PD Scientific Associate Director will:

• Serve as expert PK/PD modeler in cross-functional teams to make model-informed decisions about drug discovery, modality selection, and dose prediction.
• Integrate in vitro and in vivo data to build PK/PD, PBPK, QSP, or other mechanistic modeling platforms for drug disposition and pharmacology to support forward/reverse translation.
• Collaborate to design experimental studies and modeling plans to identify and optimize drug candidates and guide translational strategy.
• Guide automated workflows for implementing modeling platforms to inform human PK/PD and dose projections.
• Provide scientific and modeling guidance to junior colleagues.

Qualifications:

• Education: Master’s (8+ years), PharmD (6+ years), or Ph.D. (4+ years) in pharmacokinetics/pharmacodynamics, mathematics, applied mathematics, systems/computational biology, chemical/biomedical engineering, statistics/biostatistics, or related field.

Required experience/skills:

• Hands-on translational PK/PD modeling using standard software (e.g., Matlab, OSP Suite, Monolix, R) for biologics/protein therapeutics and/or peptides.
• Expert skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.

Preferred:

• Experience in interdisciplinary teams and collaborative problem scoping/planning.
• Expertise developing novel translational modeling strategies or automated workflows using PBPK, QSP, or related mechanistic modeling.

Skills:

• Biologics
• Biostatistics
• Data Analysis/Modeling/Data Science
• Drug Discovery Process
• Interdisciplinary Collaboration
• MATLAB
• Peptides
• Pharmacodynamics/Pharmacokinetics/Pharmacotherapeutics
• PK/PD Modeling
• Proteins
• Statistical Analysis
• Translational PK/PD